News — Glutathione

J. de Rey-Paihade discovered Glutathione in 1888 from extracts of yeast and many animal tissues (beef skeletal muscle and liver, fish skeletal muscle, small lamb intestine, and sheep brain). In 1921, Hopkins suggested that the philothion isolated from liver, skeletal muscle, and yeast consists of cysteine and glutamate. Still, these authors overlooked the presence of glycine in philothion, possibly due to misinterpretation of the Van Slyke amino N data. Honoring the history of the discovery of philothion, Hopkins named the substance "glutathione." Based on the content of nitrogen and sulfur in Glutathione isolated from yeast, blood, and liver. Glutathione is...